A CONSERVED ACIDIC RESIDUE IN THE C-TERMINAL FLEXIBLE LOOP OF HIV-1 NEF CONTRIBUTES TO THE ACTIVITY OF SERINC5 AND CD4 DOWNREGULATION

A Conserved Acidic Residue in the C-Terminal Flexible Loop of HIV-1 Nef Contributes to the Activity of SERINC5 and CD4 Downregulation

The host transmembrane protein SERINC5 is incorporated into retrovirus particles and inhibits HIV-1 infectivity.The lentiviral Nef protein counteracts SERINC5 by downregulating it from the cell Girls Spring Dressy Set surface and preventing its incorporation into virions.The ability of Nef to antagonize the host factor varies in magnitude between d

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Morphological characteristics and phylogenetic analyses of unusual morphospecies of Microcystis novacekii forming bloom in the Cheffia Dam (Algeria)

The toxicological potential and morphological characteristics and phylogenetic analysis based on the 16S rDNA sequence and the 16S-23S rDNA internal transcribed spacer (ITS) were investigated in unusual morphospecies of Microcystis (MCYS-CH01) isolated from the Cheffia Dam in Algeria.The presence of microcystin synthetase genes (mcyA, -B, and -C) i

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